Tag Archives: Insulin Resistance

More Rats, More Fructose, More Insulin Resistance

Rats are not humans and so care should always be taken when interpreting rodent studies. Rodent physiology differs from human physiology despite the presence of many of the same enzymes and metabolic pathways. However, rodent studies when used in conjunction … Continue reading

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More on Abdominal Obesity

Metabolic syndrome is the name given to a group of metabolic disorders that can severely affect the cardiovascular system through excessive production of free radicals generated via systemic inflammation. Abdominal fat accumulates in metabolic syndrome because of nutrient overload within … Continue reading

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Metabolic Effects of Fructose: Not Good

Evidence suggests that the cholesterol theory of cardiovascular disease is erroneous and that naturally occurring dietary lipids are not the cause of atherosclerosis. Instead, research has consistently shown that carbohydrate in the diet is the cause of cardiovascular disease. In … Continue reading

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Conjugated Linoleic Acid and Diabetes

Conjugated linoleic acid (CLA) is a group of positional and geometric isomers of the essential fatty acid linoleic acid (LA, C18:2 (n-6)). Evidence suggests that conjugated linoleic acid may be beneficial in obesity because it causes weight loss. However, this … Continue reading

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Fructose and Insulin Resistance: Evidence from Rats

Fructose is thought to be the cause of the obesity epidemic currently engulfing Western nations. Traditionally, the human diet has contained carbohydrates in their unrefined forms. Although processed through milling, the final grains product still retained the original constituents of … Continue reading

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Abdominal Fat First, Then Subcutaneous

The ‘eat-too-much, do-too-little’ theory of obesity claims that weight loss is possible through forced calorie restriction and exercise. However, neither of these things treat the cause of obesity, and for this reason both are ineffective. Obesity is a metabolic disorder … Continue reading

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Fish Oils for Type 2 Diabetes

Insulin resistance is thought to lead to the development of the metabolic syndrome, a condition characterised by serious metabolic dysfunction. One such associated abnormality is dyslipidaemia, which usually manifests itself as raised plasma levels of very low density lipoprotein (VLDL) … Continue reading

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Abdominal Adipose Tissue: Labile Store of Energy

Obesity is associated with an increased risk of disease. In particular, obesity increases the risk of developing type 2 diabetes and cardiovascular disease. Obesity is characterised by excessive adipose tissue accumulation, and it is the metabolic changes that occur with … Continue reading

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Cardiovascular Disease is a Condition of Inflammation

Proponents of the cholesterol theory of cardiovascular disease believe that dietary cholesterol is the cause of atherosclerosis. Despite a large volume of evidence that contradicts this theory it is still popular amongst mainstream medicine. The most recent research in the … Continue reading

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The Subcutaneous to Abdominal Fat Ratio

Triglycerides are stored in two main repositories of white adipose tissue in humans. A subcutaneous store is present under the skin, and this constitutes the store of fat that it visible to the exterior. In addition, humans store fat around … Continue reading

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