Category Archives: Triglycerides / Triacylglycerols

Malonyl-CoA: Pivotal In Insulin Resistance?

Posted on April 5, 2016 by Robert Barrington

Malonyl-CoA is an intermediate in the de novo synthesis of fatty acids. Stimulation of the de novo lipogenesis pathway therefore increases the production of malonyl-CoA. Malonyl-CoA is an important intermediate in this pathway because it allosterically inhibits a number of … Continue reading →

Posted in de Novo Lipogenesis, Fatty Acids, Insulin Resistance, LDL, Triglycerides / Triacylglycerols, VLDL | Comments Off

Milk Thistle Improves Glucose Metabolism

Posted on April 1, 2016 by Robert Barrington

Oxidative stress is implicated in the pathogenesis of diabetes because it may cause insulin resistance and may also cause damage to pancreatic β-cells. Milk thistle is the common name for the herb Silybum marianum, a member of the Asteraceae family … Continue reading →

Posted in Cholesterol, Glycaemia, Insulin Resistance, LDL, Liver, Milk Thistle, Silibum Marianum (milk thistle), Silymarin, Triglycerides / Triacylglycerols | Comments Off

High Carbohydrate Diets Increase Lipid Formation

Posted on March 23, 2016 by Robert Barrington

Insulin resistance is the pivotal factor in many Western lifestyle diseases. The metabolic changes that accompany insulin resistance leads to cellular dysfunction and this in turn leads to the diseases of the West, particularly obesity, cardiovascular disease and diabetes. One … Continue reading →

Posted in Carbohydrate, Fructose, Non-alcoholic Fatty Liver Disease, Protein, Starch, Sugar, Triglycerides / Triacylglycerols | Comments Off

The Fructose Fat Connection

Posted on January 22, 2016 by Robert Barrington

Chemically fructose is a hexose monosaccharide. This means is a six carbon sugar (hexose) and is not bonded to any other sugar (monosaccharide). Fructose is absorbed in the small intestine like most other sugars, and from here it passes to … Continue reading →

Posted in de Novo Lipogenesis, Fructose, Glycogen, Liver, Triglycerides / Triacylglycerols | Comments Off

Fish Oils Improve Insulin Resistance

Posted on January 21, 2016 by Robert Barrington

Fish oils are the fats obtained from fish such as mackerel, tuna, salmon and trout. They are highly polyunsaturated fatty acids that are composed primarily of eicosapentaenoic (EPA, C20:5 (n-3)) and docosahexaenoic acid (DHA, C22:6 (n-3) which belong to the … Continue reading →

Posted in Docosahexaenoic Acid, Eicosanoids, Eicosapentaenoic Acid, Fish, Fish Oils, Inflammation, Insulin Resistance, Triglycerides / Triacylglycerols, VLDL | Comments Off

Low Carbohydrate Diets Improve LDL to HDL Ratios

Posted on December 22, 2015 by Robert Barrington

Low fat diets have been shown to decrease levels of low density lipoprotein (LDL) cholesterol, whilst low carbohydrates have been shown to increase LDL cholesterol. Elevated levels of LDL have traditionally been seens as a risk factor for cardiovascular disease … Continue reading →

Posted in Carbohydrate, Cardiovascular Disease, Cholesterol, HDL, LDL, Triglycerides / Triacylglycerols, VLDL | Comments Off

Low Carbohydrate Diets Lower Fasting Plasma Triglycerides

Posted on December 21, 2015 by Robert Barrington

Low carbohydrates diets appear to be effective in treating obesity. This may relate to the ability of such diets to improve insulin sensitivity. If this hypothesis is correct, it would be expected that such diets would be effective because they … Continue reading →

Posted in Carbohydrate, de Novo Lipogenesis, Fructose, Triglycerides / Triacylglycerols, VLDL, Weight Loss | Comments Off

Insulin Resistance and Nonalcoholic Fatty Liver

Posted on December 15, 2015 by Robert Barrington

Nonalcoholic fatty liver disease (NAFLD) is a recently identified phenomenon, whereby the liver becomes diseased through a mechanisms that is independent of alcohol consumption. Nonalcoholic fatty liver disease is almost identical pathologically to alcoholic fatty liver disease, but while the … Continue reading →