Monthly Archives: June 2012

Molybdenum Kinetics

Posted on June 10, 2012 by Robert Barrington

Molybdenum is an essential element in humans that is required for the enzymes xanthine oxidase, xanthine dehydrogenase, sulfite oxidase and aldehyde oxidase. The xanthine enzymes are involved in the hydroxylation of heterocyclic nitrogen compounds such as purines, whereas sulfite oxidase … Continue reading →

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Chromium and the Relationship to Insulin

Posted on June 9, 2012 by Robert Barrington

The association between chromium deficient diets and hyperglycaemia in rats and mice has been well reported, and the role of chromium in animal nutrition has been extensively researched. Less is known about the role of chromium in humans, partly because … Continue reading →

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Calcium Blood Pressure

Posted on June 8, 2012 by Robert Barrington

Hypertension is a leading risk factor for cardiovascular disease and yet divisions and controversy still surround its causes. The role of sodium intake in the development of hypertension has been supported by the mainstream medical authorities in Western nations for … Continue reading →

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Weight Loss and Calcium Absorption

Posted on June 7, 2012 by Robert Barrington

The role played by calcium in maintaining correct bodyweight has been extensively reported in the literature. Epidemiological studies suggest an inverse association between calcium intakes and bodyweight, and both clinical trials and animal models show that calcium feeding is able … Continue reading →

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Peptides that Regulate Feeding Behaviour: The Orectic Peptides

Posted on June 6, 2012 by Robert Barrington

As discussed previously (here), there are a number of peptides that have been identified within mammals that regulate feeding behaviour. Anorectic peptides that act to reduce food intake include insulin, leptin, somatostatin, bombesin, calcitonin, cholecystokinin, corticotrophin releasing factor and peptide … Continue reading →

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Peptides that Regulate Feeding Behaviour: The anorectic Peptides

Posted on June 5, 2012 by Robert Barrington

Peptides that regulate appetite have been identified in the tissues of the gastrointestinal tract, pituitary, pancreas, hypothalamus and general neural tissues of mammals. These peptides tend to show paracrine, autocrine and endocrine functions that synergistically allows the regulation of energy … Continue reading →

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The Calcium Paradox Disease

Posted on June 4, 2012 by Robert Barrington

That calcium is involved in the proper regulation of body weight is now well established in the scientific literature and this topic has been extensively reviewed1,2,3,4. While the inverse association between calcium and body weight is fairly well reported, the … Continue reading →

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The Mechanisms of Calcium Induced Weight loss

Posted on June 3, 2012 by Robert Barrington

Calcium is an important macromineral that in its ionic form (Ca2+) plays an important role as an intracellular signal molecule. The main source of calcium in most Western diets is dairy produce, with sources including milk, yogurt and cheese. Traditionally, … Continue reading →

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Is Obesity Really Caused by a Positive Energy balance?

Posted on June 2, 2012 by Robert Barrington

Obesity is a complex condition that involves the interaction of multiple genetic and environmental factors. Despite this complexity, the cause of obesity is often oversimplified to a condition of a positive energy balance. A small but consistent overconsumption of energy, … Continue reading →

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More on Chromium Excretion

Posted on June 1, 2012 by Robert Barrington

Researchers1 have investigated the effects of chromium chloride supplementation on the excretion of chromium in free-living subjects. At baseline, the urinary excretion of chromium was 0.20µg/d and 0.17µg/d in 15 healthy female and 27 healthy male subjects, respectively. The authors … Continue reading →

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