Category Archives: Syndrome X

Red Meat and Metabolic Syndrome

The metabolic syndrome increases the risk of developing diabetes and is characterised by insulin resistance, systemic inflammation, abdominal obesity and alterations to blood lipoprotein levels. High levels of fructose in the diet are associated with metabolic syndrome, because fructose is … Continue reading

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Fructose and Uric Acid

High quantities of fructose in the diet are able to increase circulating VLDL-triglyceride levels because fructose metabolism by the liver increases the rate of de novo lipogenesis. One hypothesis suggests that these fatty acids contribute to insulin resistance because they … Continue reading

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Fructose Consumption

Fructose is of interest because evidence links high consumption to metabolic syndrome and obesity. Increases in fructose consumption are illustrated by information from history and anthropology. In 1000 AD, sucrose (50% fructose) consumption was very low and few Europeans were … Continue reading

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Inflammation, Saturated Fat and Insulin Resistance

White adipose tissue has an endocrine function that can regulate energy balance, glucose homeostasis and immune function. Obesity is increasingly being seen as a disease of chronic inflammation that results from the effect of excess saturated fat on white adipose … Continue reading

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de Novo Lipogenesis and Carbohydrates

Metabolic syndrome (syndrome X) is characterised by insulin resistance and can lead to obesity. The cause of the insulin resistance in metabolic syndrome is not completely understood, but fructose is thought to play a part in its development. Fructose is … Continue reading

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Risk Factors for Metabolic Syndrome

Metabolic syndrome (syndrome X) is characterised by the development of insulin resistance, abdominal weight gain and hyperlipidaemia, which can increase the risk of cardiovascular disease. Lifestyle choices are known to be contributory factors in the development of metabolic syndrome. Research1 … Continue reading

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Blueberries Lower Cardiovascular Risk

Blueberries are a good source of phenolic compounds, and evidence suggests that plant polyphenols may reduce the risk of cardiovascular disease. In particular, blueberries are rich in anthocyanins (93 to 235 mg / 100g berries), a sub-group of flavonoids that … Continue reading

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High Fructose Corn Syrup

Increases in the use of high fructose corn syrup (HFCS) as a sweetener mirror the rise in obesity seen in Western nations over the last four decades. High fructose corn syrup is produced by isomerising a large proportion of the … Continue reading

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Obesity and Cardiovascular Disease

Obesity is know to be a risk factor for cardiovascular disease. However, obesity is complex and its aetiology is not fully understood. It is known that a positive energy balance in addition to development of the metabolic syndrome (syndrome X) … Continue reading

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Insulin Resistance and Muscle Lipids

Obesity levels are rising in Western nations and research implicates the development of metabolic syndrome as the main cause of the epidemic. Metabolic syndrome, also called syndrome X, is a condition characterised by resistance of muscle cells to the effects … Continue reading

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