Category Archives: Leucine

How Does Protein Build Muscle?

Posted on September 9, 2019 by Robert Barrington

Skeletal muscle is made up predominantly of protein. When we eat animal flesh we are eating their muscle, along with any associated fat and a small amount of carbohydrate stored in skeletal muscle as glycogen. Skeletal muscle is made up … Continue reading →

Posted in Branched Chain Amino Acids, Leucine, Protein, Skeletal Muscle | Comments Off on How Does Protein Build Muscle?

Protein and Vitamin D For Strength in Old Age?

Posted on November 21, 2017 by Robert Barrington

Fat free mass is inversely associated with mortality. This relates in part to the fact that as people age muscle mass naturally decreases, which is in part caused by the natural reduction in hormones including growth hormone, testosterone and insulin … Continue reading →

Posted in Leucine, Mortality, Protein, Skeletal Muscle, Vitamin D | Comments Off on Protein and Vitamin D For Strength in Old Age?

Whey Protein: The Leucine Threshold

Posted on August 4, 2017 by Robert Barrington

Powdered whey protein is a useful supplement. It provides a simple and cost effective solution to those wishing to increase protein intake. Whey protein holds a number of advantages over other proteins, and in particular, the proteins in whey have … Continue reading →

Posted in Branched Chain Amino Acids, Leucine, Resting Metabolic Rate (RMR), Skeletal Muscle, Whey Protein | Comments Off on Whey Protein: The Leucine Threshold

The Bioavailability of HMB

Posted on May 4, 2016 by Robert Barrington

β-hydroxy-β-methylbutyrate (HMB) is a metabolite of the essential and branched chain amino acid L-leucine. Leucine is metabolised to HMB in a two step reaction first to α-ketoisocaproate (KIC) and then to isovaleryl-CoA. This transamination pathway accounts for around 10 % … Continue reading →

Posted in Exercise, Hydroxy-methyl-butyrate (HMB), L-leucine, Leucine, Skeletal Muscle | Comments Off on The Bioavailability of HMB

Roughly 50 Essential Factors

Posted on January 30, 2016 by Robert Barrington
Posted in Biotin, Calcium, Chromium, Cobalamin, Cobalt, Essential Amino Acids, Essential Fatty Acids, Fluoride, Glucose, Iron, L-leucine, L-lysine, L-methionine, L-phenylalanine, L-theanine, L-tryptophan, Leucine, Macrominerals, Magnesium, Manganese, Molybdenum, Niacin, Nickel, Pantothenic Acid, Phosphorus, Riboflavin, Selenium, Sodium, Starch, Thiamine, Trace Minerals, Vanadium, Vitamin A, Vitamin B, Vitamin C, Vitamin D, Vitamin E, Vitamin K, Zinc | Comments Off on Roughly 50 Essential Factors

The Muscle Building Effects of Leucine

Posted on May 6, 2015 by Robert Barrington

Protein supplementation enhances the synthesis of skeletal muscle protein. Such myofibrillar protein synthesis is thought to occur through activation of a signal cascade involving rapamycin-1 complex (a protein kinase that regulates cell growth, protein synthesis and cell proliferation amongst other … Continue reading →

Posted in Branched Chain Amino Acids, Essential Amino Acids, Exercise, Hydroxymethybutyrate (HMB), Leucine, Protein, Resistance Training, Skeletal Muscle, Whey Protein | Comments Off on The Muscle Building Effects of Leucine

Biotin and Leucine Metabolism

Posted on December 7, 2012 by Robert Barrington

Conversion of 3-methylcrotonyl CoA to 3-methylglutaconyl CoA is a metabolic step in leucine catabolism pathway that is catalysed by the enzyme methylglutaconyl CoA carboxylase (MCC). Biotin is required as a cofactor for the MCC enzyme, and marginal biotin deficiency reduces … Continue reading →

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Whey Protein and Muscle Protein Synthesis

Posted on September 11, 2012 by Robert Barrington

Protein can have very different physiological effects depending on its source, and these differences relate to the varying amino acid profiles as well as the speed of digestion. For example, casein and whey protein are two milk proteins with very … Continue reading →

Posted in Branched Chain Amino Acids, Exercise, Insulin, Leucine, Protein, Whey Protein | Comments Off on Whey Protein and Muscle Protein Synthesis