Quercetin to Treat Anxiety?

Quercetin is a phytochemical that belongs to the flavonol sub-group of flavonoids. The molecule is hydroxylated three times, and each hydroxyl group can interact with a free radical to reduce oxidative stress. This gives quercetin a good antioxidant potential, and may explain its therapeutic benefits. One such benefit is the ability to positively affect mood and to protect neuronal health. A number of studies have been performed that provide evidence for this claim. For example, in one animal study mice were exposed to stress through deliberate immobilisation (something they do not like and which causes anxiety) and then provided with behavioural tasks. When the mice were administered quercetin, the behaviour they exhibited in these tasks could be described as  less anxious than animals with no quercetin. Analysis of tissues from the quercetin mice showed that a significant antioxidant effect had occurred. Therefore quercetin may provide protection from mood disorders through its ability to reduce oxidative stress. 

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Samad, N., Saleem, A., Yasmin, F. and Shehzad, M. A. 2018. Quercetin protects against stress-induced anxiety-and depression-like behavior and improves memory in male mice. Physiological Research. 67(5): 795-808

About Robert Barrington

Robert Barrington is a writer, nutritionist, lecturer and philosopher.
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