The brain contains large amounts of lipids, which are located particularly in the cell membranes of neurones. The lipid in the diet can directly influence the fat in the brain, and it has been shown for example that diets high in omega-3 fatty acids can increase the omega-3 fat content of the brain significantly. This diet to brain connection is important because the localised fats and lipids in the cell membranes play a significant role in determining the number and function of proteins on the surface of the cell membranes. These proteins are pivotal in the signal cascades that occur in the brain when neurones fire as they act as enzymes, transporters and receptors. A poor diet can disrupt the normal lipid content of the brain, and if the diet is particularly deficient in important lipids. there is the possibility that brain function will be significantly detrimentally affected. As well as omega-3 fats, glycerolipids, glycerophospholipids, and sphingolipids have all been evidenced to be able to significantly affect brain function.
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