Category Archives: Glucagon-like Peptide 1

The SGLT1 Cotransporter and Gastric Emptying

Gastric emptying may be an important determinant of the glycaemic effect of food. Because lower a glycaemic load is associated with protection from weight gain, diabetes and cardiovascular disease, nutritional factors that can inhibit or delay gastric emptying are of … Continue reading

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The Glycaemic Index

The effect that a particular carbohydrate food has on the postprandial plasma blood glucose concentration can be assessed and quantified using the glycaemic index (GI). Foods that elicit a low postprandial rise in blood sugar levels can be said to … Continue reading

Posted in Cancer, Carbohydrate, Cardiovascular Disease, Diabetes, Gastric Inhibitory Peptide (GIP), Glucagon-like Peptide 1, Glucose, Glycaemic Index, Glycaemic load, Metabolic Syndrome | Comments Off on The Glycaemic Index

Incretin Secretion

Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are incretin hormones secreted in response to food in the gut. These hormones are able to potentiate the glucose stimulated release of insulin in a response called the incretin effect. The … Continue reading

Posted in Carbohydrate, Fat, Gastric Inhibitory Peptide (GIP), Glucagon-like Peptide 1, Glucose, Incretins, Insulin, Protein | Comments Off on Incretin Secretion

Chewing and Energy Intake

Traditionally, obesity has been thought of as a simple energy imbalance, whereby calorie intake becomes too great when compared to the amount of energy expended on metabolic processes and physical activity. However, within the last decade, a picture is emerging … Continue reading

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Breakfast Affects Subsequent Feeding Habits

Reports suggest that decreasing numbers of people are consuming breakfast regularly, and yet at the same time evidence suggests that breakfast may be protective of obesity. For example, epidemiological studies have reported that regular consumption of breakfast is associated with … Continue reading

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Glutamine and Insulin

Metabolic dysfunction regarding the insulin system is thought to lead to insulin resistance, metabolic syndrome, obesity, type 2 diabetes and hyperglycaemia. The insulin system is complex and not fully understood, but recent advances have uncovered further details of its mode … Continue reading

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Resistant Starch

Resistant starch is the fraction of starch not digested enzymatically in the small intestine. Resistant starch is considered a form of dietary fibre bacause it passes to the colon where bacterial degradation causes its conversion to short-chain fatty acids (SCFA). … Continue reading

Posted in Fibre, Gastric Inhibitory Peptide (GIP), Glucagon-like Peptide 1, Insulin, Resistant Starch, Retrogradation | Comments Off on Resistant Starch

Peptides that Regulate Feeding Behaviour: The Orectic Peptides

As discussed previously (here), there are a number of peptides that have been identified within mammals that regulate feeding behaviour. Anorectic peptides that act to reduce food intake include insulin, leptin, somatostatin, bombesin, calcitonin, cholecystokinin, corticotrophin releasing factor and peptide … Continue reading

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Viscosity of Drinks and Gut Hormones

A number of gut peptides are known to be involved in inducing a feeling of satiety and reducing further food intake. Many of theses act locally on the gastrointestinal tract, but others enter circulation and act on the central nervous … Continue reading

Posted in Beta glucans, Cholecystokinin, Fibre, Ghrelin, Glucagon-like Peptide 1, Peptide YY | Comments Off on Viscosity of Drinks and Gut Hormones

Amino Acids and Insulin

The relationship between dietary carbohydrates and insulin is well researched. The quantity and type of carbohydrate food ingested affect the rate at which the food is digested and enters the blood circulation. Insulin is required for the uptake of glucose … Continue reading

Posted in Branched Chain Amino Acids, GIP, Glucagon-like Peptide 1, Insulin | Comments Off on Amino Acids and Insulin