Insulin Resistance and Depression

Insulin resistance causes widespread metabolic changes that lead to significant disease development, including mood disorders. Insulin resistance is an underlying factor in the development of diabetes and it is known that diabetic individuals are at a higher risk of developing mood disorders such as depression, compared to non-diabetic individuals. Studies have demonstrated a positive correlation between the development of insulin resistance and the development of depression but care must be taken when considering the cause and effect. It is known that insulin has a large number of functions in the brain and so it stands to reason that a dysfunction in the insulin system could trigger mental health problems. Alternatively, another factor related to both mental health and insulin resistance could be causative. One thing is clear, a healthy lifestyle, that includes a healthy diet, is able to protect from both depression and insulin resistance, giving a clue that poor diet could be the controlling factor. 

Eat Well, Stay Healthy, protect Yourself


Timonen, M., Laakso, M., Jokelainen, J., Rajala, U., Meyer-Rochow, V. B. and Keinänen-Kiukaanniemi, S. (2004). Insulin resistance and depression: cross sectional study. British Medical HJournal. 330(7481): 17-18

About Robert Barrington

Robert Barrington is a writer, nutritionist, lecturer and philosopher.
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