Annona diversifolia is a plant used in traditional Mexican herbal medicine for the treatment of nervios. Nervios in Latin America is considered a state of bodily and mental unrest, possibly as caused by stress. One aspect of nervios that is well characterised in the detrimental effects on the mood of the individual. Annona diversifolia is useful in the treatment of the mood component of nervios, which suggests that it may have anxiolytic and antidepressant activity. Researchers have identified palmitone, an aliphatic ketone, as the active principle that may give Annona diversifolia its mood elevating properties. For example, in one study, researchers administered plamitone to mice and exposed them to experimental stress. In comparison to control animals who were administered no plamitone, the treatment mice exhibited more explorative behaviour indicating a reduction in anxiety, which produced no sedative effects in the mice at the dose used. Therefore palmitone from Annona diversifolia may have significant anxiolytic effects.
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