Category Archives: Leptin

More on Leptin

Posted on April 11, 2012 by Robert Barrington

Leptin is a 167 amino acid protein involved in an endocrine circuit that regulates energy homeostasis. The importance of leptin in energy regulation was not appreciated until 1994, when studies involving ob/ob and db/db genetic mouse strains were performed. These … Continue reading →

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The Regulation of Energy Balance

Posted on January 5, 2012 by Robert Barrington

Despite daily fluctuations in energy intake, energy balance is maintained in humans such that body weight can remain constant for long periods of time. The maintenance of a constant body weight occurs because the body has a sensitive homeostatic feedback … Continue reading →

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Diet and Exercise Lowers Leptin Levels

Posted on October 28, 2011 by Robert Barrington

Leptin is a 16 kDa peptide that is secreted from white adipose tissue in proportion to the size of the fat mass in humans and other mammals. Leptin binds to receptors in the hypothalamus and decreases food intake and increases … Continue reading →

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Food: Pleasure or Fuel?

Posted on July 14, 2011 by Robert Barrington

Food is needed for survival as it provides the chemical energy required for movement and metabolism. However, some foods are sought particularly for their pleasurable sensation and highly palatable tastes. Researchers split the two contrasting regulatory mechanism of feeding into … Continue reading →

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Leptin

Posted on July 9, 2011 by Robert Barrington

Obesity is caused by a combination of metabolic defect and long term imbalance between energy intake and energy expenditure. Leptin plays an important role in the regulation of food intake, and therefore it is of great interest to nutritional scientists … Continue reading →

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