Selenium is an essential trace mineral needed by the cells of the body for a number of functions. In particular, selenium forms part of the enzyme glutathione peroxidase, and in this role is required for antioxidant protection. Evidence suggests that selenium is able to prevent the damaging effects of stress in the brain through its role as an antioxidant. Stress is particularly damaging to the brain because of the high levels of polyunsaturated fatty acids in brain tissue. These are susceptible to free radicals and oxidative stress can cause long term effects that damage brain tissue and prevent the brain from functioning correctly. This may be a significant cause of mood disorders. Selenium is able to prevent this damage through its ability to regulate oxidative stress. This supports evidence that selenium supplementation is effective against mood disorders and may be able to reduce the risk of depression and anxiety. As selenium levels in the diet may vary, a selenium supplement is recommended to maintain optimal selenium status.
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