Resveratrol and Mood

Resveratrol is a polyphenol found in the skins of red grapes and therefore red wine is a rich source. Resveratrol is an antioxidant and anti-inflammatory, and studies show that it may confer a number of health effects. One aspect of the health effects of resveratrol are the cognitive and neuroprotective effects that it possesses. Animal models show a range of cognitive effects as well as protection from mood disorders in animals models of anxiety and depression. In humans the effects of resveratrol on cognition are less well evidenced and this may relate to the design of the studies, nuances in the way cognition is measured in humans versus animals, as well as a myriad of other factors. However, studies in humans do show clear evidence of the ability of resveratrol to elevate mood. The mood elevating effects of resveratrol may relate to its antioxidant and anti-inflammatory effect, both of which are protective of the development of anxiety and depression. Both grapes and red wine may therefore be protective of mental health. 

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Farzaei, M. H., Rahimi, R., Nikfar, S. and Abdollahi, M. 2018. Effect of resveratrol on cognitive and memory performance and mood: A meta-analysis of 225 patients. Pharmacological Research. 128: 338-344

About Robert Barrington

Robert Barrington is a writer, nutritionist, lecturer and philosopher.
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