More on Protein, L-Tryptophan and Depression

Stress is thought to increase the risk of depression because it causes brain changes that lead to an inadequate supply of certain neurotransmitters, particularly serotonin. One strategy to treat depression revolves around attempting to increase the availability of serotonin, either through reducing its destruction or increasing it synthesis. Dietary L-tryptophan may allow increased synthesis of serotonin when serotonin levels are lowered as in depression. One study showed that a tryptophan rich hydrolysed protein drink was significantly able to lower the cortisol response to stress in a group of individuals. Further the tryptophan rich hydrolysate was significantly able to improve the mood of the individuals. Therefore dietary protein that contains L-tryptophan may be a useful tool in the treatment of depression. Further this shows the influence that diet can have on depression, and suggests that a diet high in protein may confer significant protection against the development of poor mental health and mood disorders. 

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Firk, C. and Markus, C. R. 2009. Mood and cortisol responses following tryptophan-rich hydrolyzed protein and acute stress in healthy subjects with high and low cognitive reactivity to depression. Clinical Nutrition. 28(3): 266-271

About Robert Barrington

Robert Barrington is a writer, nutritionist, lecturer and philosopher.
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