More on Creatine and Mood

Creatine supplements may have mood elevating and cognitive effects. The reason for this is the ability of creatine to increase the energy capacity of brain cells. The mood elevating and cognitive enhancing effects of creatine make it a potentially useful treatment for dementia, where cognition and mood become depressed. A number of studies have investigated the effects of creatine on dementia in humans subjects. For example, in one study researchers administered 20 grams per day of creatine monohydrate for 6 days followed by 2 grams per day of creatine monohydrate for 6 months to a group of individuals with Parkinson’s disease. The results of the study showed that there was an increase in the uptake of creatine into the brains of the patients. Further, creatine also caused an improvement in mood in the patients, supporting other studies that suggest that creatine has mood elevating properties. In addition the creatine also caused a small improvement in the effects of the dopaminergic medication being used by the patients.  

Eat Well, Stay Healthy, Protect Yourself


Bender, A., Koch, W., Elstner, M., Schombacher, Y., Bender, J., Moeschl, M., Gekeler, F., Muller-Myhosok, B., Gasser, T., Tatsch, K. and Klopstock, T. 2006. Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial. Neurology.  67(7): 1262-1264

About Robert Barrington

Robert Barrington is a writer, nutritionist, lecturer and philosopher.
This entry was posted in Anxiety, Creatine, Dementia, Depression, Mood. Bookmark the permalink.