Ipomoea stans (Tumbavaqueros): Mexican Anxiety Treatment?

weight lossIn Mexico, Ipomoea stans  is referred to as Tumbavaqueros. Tumbavaqueros is used in Mexican traditional medicine for its central nervous system activity. In this regard, Tumbavaqueros is used as a sedative, anti-seizure and for treating headaches. Studies have investigated the pharmacological effects of Tumbavaqueros using animal models. For example, in one study researchers administered root extracts of Tumbavaqueros to mice and exposed them to experimental stress. The results of the study showed that the extracts were significantly effective at reducing the anxiety experienced by the mice. In addition, the root extract was also effective at reducing drug induced convulsions in the mice and was shown to have a sedative action. Therefore the experimental evidence support the traditional uses of the herb, and there appears to be significant central nervous system effects for root extracts of Tumbavaqueros in animals.

Ipomoea stans (Tumbavaqueros) anxiety depression

Tumbavaqueros contains a number of phytochemicals that may explain its effects on the central nervous system. In particular, a group of resin glycosides, tetrasaccharide glycosides called tyrianthins 1 to 7, and glycolipids have been identified as potentially being responsible for the pharmacological effects of the plant. For example administration of tyranthin 6 to mice cause antidepressant effects.

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Herrera-Ruiz, M., Gutiérrez, C., Jiménez-Ferrer, J. E., Tortoriello, J., Mirón, G. and León, I. 2007. Central nervous system depressant activity of an ethyl acetate extract from Ipomoea stans roots. Journal of Ethnopharmacology. 112(2): 243-247
Mirón-López, G., Herrera-Ruiz, M., Estrada-Soto, S., Aguirre-Crespo, F., Vázquez-Navarrete, L. and León-Rivera, I. 2007. Resin glycosides from the roots of Ipomoea tyrianthina and their biological activity. Journal of Natural Products. 70(4): 557-562

About Robert Barrington

Robert Barrington is a writer, nutritionist, lecturer and philosopher.
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