Ficus racemosa: Lipase Inhibitor

Dietary fats are a mixture of triglycerides, and their absorption is through the lymphatic system following enzymatic hydrolysis by lipase to fatty acids, monoglycerides and glycerol. Inhibition of the lipase enzyme in the gut has been shown to decrease fat absorption from meals, and some manufacturers have marketed and sold lipase inhibitors for the purpose of weight loss. Ficus racemosa is an evergreen deciduous tree, belonging to the family Moraceae which is found throughout Asia, Africa, America and Australian. Studies suggest that Ficus racemosa possesses significant antihyperlipidaemic effects, and this may result from the presence of significant amounts of lipase inhibiting phytochemicals within the plant tissues. In one study researchers separated a number of phytochemicals from the plant and showed that one chemical, diethyl Phthalate, may possess inhibitory effects on the enzyme. pancreatic lipase. The fruit contained the highest amounts of the lipase inhibitor, but it was present in other parts of the plant. 

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Anand, A. V., Bharathi, V., Bupesh, G., Lakshmi, J., Sundaram, K. M. and Saradhadevi, M. 2021. Identification of novel potent pancreatic lipase inhibitors from Ficus racemosa. Biomedicine. 41(1): 23-30

About Robert Barrington

Robert Barrington is a writer, nutritionist, lecturer and philosopher.
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