Euphorbia hirta is a plant belonging to the Euphorbiaceae family of pants. Extracts of the plant is used in traditional medicine, often for gastrointestinal complaints. The plant grows as a small shrub and is often considered a weed. Investigations into the pharmacological activity of extracts of the plant show that components within the plant are bioactive, and may have particular effects at altering brain chemistry. This may explain the anxiolytic and sedative effects of the plant. Evidence suggests that extracts of Euphorbia hirta may affects a number of neurotransmitter systems in the brain. For example, in chronically stressed rats, acetylcholine levels fall in frontal cortex, hippocampus and septum of the brain. However Euphorbia hirta can attenuate the reductions acetylcholine seen in these regions. Euphorbia hirta may therefore be able to prevent changes in brain chemistry seen during chronic stress and this may explain the anxiolytic and antidepressant effects of the plant.
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