Category Archives: Pyridoxine

Folic Acid Deficiency: The Cardiovascular Disease Link

Posted on March 5, 2015 by Robert Barrington

Homocysteine is a product of cellular methionine metabolism. Evidence suggests that high levels of plasma homocysteine are a risk factor for cardiovascular disease. Homocysteine may interfere with endothelial physiology through inhibition of nitric oxide synthesis, inducing endothelial dysfunction possibly via … Continue reading →

Posted in Cobalamin, Endothelial Dysfunction, Folate, Homocysteine, Nitric Oxide, Oxidative Stress, Pyridoxine, Vitamin B | Comments Off on Folic Acid Deficiency: The Cardiovascular Disease Link

B Vitamin Status of Hypercholesterolaemic Men

Posted on March 2, 2015 by Robert Barrington

Elevated levels of plasma homocysteine are an independent risk factor for cardiovascular disease because homocysteine can cause damage to the endothelial linings of arteries. Homocysteine in humans can be metabolised to a number of different compounds and these metabolic steps … Continue reading →

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Vitamin C Interactions With Vitamin B6

Posted on January 28, 2015 by Robert Barrington

Vitamin C is perhaps the most well known vitamin amongst the general population and vitamin C supplements are widely available, cheap and popular. Evidence from the nutritional literature that vitamin C in gram amounts is beneficial at preventing infection and … Continue reading →

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Are Eggs Good For The Heart?

Posted on January 4, 2015 by Robert Barrington

Eggs have been part of the human diet since the chicken was first domesticated in Asia over 4000 years ago. Many people believe that eggs are detrimental to the health because they are energy (calorie), saturated fat and cholesterol dense. … Continue reading →

Posted in Betaine, Cardiovascular Disease, Choline, Cobalamin, Eggs, Folate, Pyridoxine, Vitamin B | Comments Off on Are Eggs Good For The Heart?

28 Days Later: Vitamin B6 Deficiency

Posted on November 21, 2014 by Robert Barrington

Vitamin B6 is an essential nutrient in humans. This means it cannot be synthesised endogenously, but instead must be present in the diet. Once absorbed vitamin B6 is converted to its active form through addition of a phosphate molecule, forming … Continue reading →

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The Betaine Folate Relationship

Posted on June 7, 2014 by Robert Barrington

Epigenetics is the relatively new science interested in the interaction between the environment and DNA. Environmental changes can influence genetic make-up through stable modification to gene expression not mediated by changes in DNA sequence. This is achieved through methylation of … Continue reading →

Posted in Betaine, Choline, Cobalamin, Folate, Homocysteine, Pyridoxine, Vitamin B | Comments Off on The Betaine Folate Relationship

Pyridoxal Phosphate Inhibited By Theophylline

Posted on January 29, 2014 by Robert Barrington

Pyridoxal phosphate is the activated version of pyridoxal, part of the vitamin B6 group of vitamins (here). The vitamin functions in a large number of reactions as a cofactor for amino acid metabolism. Low plasma levels of pyridoxal phosphate are … Continue reading →

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Vitamin B6 Supplements in Pregnancy

Posted on January 20, 2014 by Robert Barrington

  We are told by medical experts that vitamin supplements are not necessary and we acquire all the nutrients we need from food. In fact the more cynical amongst us may claim that there is even the possibility of a … Continue reading →

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Vitamin B6: Ethanol Inhibits Absorption

Posted on December 21, 2013 by Robert Barrington

Pyridoxine (vitamin B6: here) is a group of related chemicals that play an important role as coenzymes in energy metabolism in humans. Dietary pyridoxine is absorbed to enterocytes of the gut and then phosphorylated to pyridoxal 5’-phosphate, the active coenzyme … Continue reading →

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