Category Archives: Leptin Resistance

More On Leptin Resistance

Leptin is a peptide hormone that is produced in adipocytes. The circulating levels of leptin are proportional to the amount of body fat. Circulating leptin levels therefore increase in obese individuals, as blood leptin levels rise concomitantly with adiposity. Leptin … Continue reading

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The Leptin Story

Leptin is a peptide hormone that was discovered in 1994 by a Scientist called Friedman. Fat cells produce leptin and this signal is used in a feedback loop to allow the maintenance of correct body weight. Mice missing the leptin … Continue reading

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Does Exercise Cause Fat Loss Because It Builds Muscle?

Many experts and laypersons alike believe that weight gain is caused by eating too much and doing too little. This ‘eat-too-much, do-too-little’ theory of weight gain is so ingrained in the mindset of the general population that it is almost … Continue reading

Posted in Aerobic Exercise, Energy Expenditure, Exercise, Insulin Resistance, Leptin Resistance, Obesity, Resistance Training, Resting Metabolic Rate (RMR), Skeletal Muscle, Testosterone, Weight Loss | Comments Off on Does Exercise Cause Fat Loss Because It Builds Muscle?

Obesity As A Disease Of Starvation

Like many biological phenomenon, feeding behaviour is reliant on a negative feedback loop. This loop involves the detection of food in the gut and nutrients in the blood and a subsequent neuronal and hormonal response that corrects behaviour. A loop … Continue reading

Posted in Insulin, Insulin Resistance, Leptin, Leptin Resistance, Micronutrients, Obesity, Protein, Trace Minerals, Traditional Diets, Western Diet | Comments Off on Obesity As A Disease Of Starvation

Overweight? Get Your Zinc

Obesity is characterised by metabolic dysfunction that includes insulin and leptin resistance. This dysfunction leads to a derailing of normal appetite and energy regulation and this results in hyperphagia and reductions in resting, postprandial and post-exercise metabolic rates. This is … Continue reading

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The Obesity Paradox (Addendum)

The obesity paradox describes the apparent contradiction that despite a large energy intake and massive fat reserves, the obesity disease is perceived by the hypothalamus as one of starvation. This explains the total failure of calorie restriction and exercise to … Continue reading

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Starvation State Following Weight Loss

Mainstream propaganda claims that obesity is caused by laziness and greed. This propaganda originates from the food industry and their paid agents. It is important for the food industry to convince the population that the food they eat is safe. … Continue reading

Posted in Abdominal Obesity, Leptin Resistance, Obesity | Comments Off on Starvation State Following Weight Loss