Category Archives: Gamma Linolenic Acid

GLA and EPA Interaction

Starflower (borage) and evening primrose oils are good sources of the n-6 long chain polyunsaturated fatty acid γ-linolenic acid (GLA, C18:3 (n-6)). In humans GLA is converted to dihomo-γ-linolenic acid (DGLA, C20:3 (n-6)) which is subsequently converted to the anti-inflammatory … Continue reading

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More on GLA and Inflammation

The essential fatty acids α-linolenic acid (ALA, C18 (n-3)) and linoleic acid (LA, C18:2 (n-6)) play an important role in the formation of eicosanoids. Eicosanoids are 20-carbon chemicals that act as local hormones to regulate cellular inflammation. Eicosanoids can be … Continue reading

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Important Long Chain Fatty Acids

There are a number of long chain fatty acids that are important to human health (figure 1). The essential fatty acids alpha-linolenic (ALA, C18:3 (n-3)) acid and linoleic acid (LA, C18:2 (n-6)) cannot be synthesised by humans but are vital … Continue reading

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Essential Fatty Acids in Skin

Skin conditions are associated with n-6 fatty acids but generally not with n-3 fatty acid. The result of n-6 deficiency is increased inflammation, which includes heat, pain, redness, swelling, and loss of function. This can cause weeping, increased proliferation of … Continue reading

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Fatty Acids, Eicosanoids and Arachidonic Acid

Alpha linolenic acid (ALA) and linoleic acid (LA) are polyunsaturated fatty acids (PUFA) of the omega 3 and 6 family respectively, and are both essential to health. These fatty acids have a number of important function in humans, and deficiency … Continue reading

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Synergism Between Essential Fats

Gamma-linolenic acid (GLA, C18:3 (n-6)) is a fatty acid that is synthesised in humans from the essential fatty acid linoleic acid (LA, C18:2 (n-3)). Addition of GLA to the diet of humans can reduce inflammation in conditions such as rheumatoid … Continue reading

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