Category Archives: Free Radicals

Plasma Antioxidants Associated with Insulin Sensitivity

Insulin resistance is characterised by an increase in the fasting plasma levels of insulin and glucose, and this is caused by a reduction in the efficiency of the insulin signalling system in the peripheral tissues. The development of insulin resistance … Continue reading

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The Oxidative Stress Theory of Insulin Resistance

Insulin resistance is a state whereby the insulin receptor become insensitive to the effects of insulin. As a result blood glucose levels remain elevated even in the fasted state. The presence of glucose in the blood postprandially, when normally levels … Continue reading

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Nitrosamine in Processed Meat May Cause Insulin Resistance

Insulin resistance is now implicated in the development of a number of Western lifestyle diseases including type 2 diabetes, obesity and cardiovascular disease. In addition, deleterious changes to the brain, that can result in dementia may also be caused by … Continue reading

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Why Do Oxidised Fats and Oils Contribute to Insulin Resistance?

Oxidised oils and fats are damaging to the health because when ingested, they are absorbed and interact with tissues causing the initiation free radical chain reactions. This creates oxidative stress in the cells and tissues of the body and in … Continue reading

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Insulin Resistance And Oxidative Stress

Insulin resistance is a likely driver of weight gain. Insulin resistance is characterised by a deterioration of the strength of the signal elicited by insulin on the cell, and as a result the insulin signal becomes less efficient at stimulating … Continue reading

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Is Oxidative Stress The Main Driver of Insulin Resistance?

Obesity, cardiovascular disease and type 2 diabetes are all aetiologically linked through the metabolic syndrome. The observation that all three diseases are associated with oxidative stress, has lead some to speculate that oxidative stress is the causative factor in metabolic … Continue reading

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Oxidised Oils

As well as trans fats the typical Western diet also contains a group of oils called the oxidised fats. Like all biomolecules, fats can react with a number of substances to produce derivatives that change their chemical and physical properties. … Continue reading

Posted in Fatty Acids, Fish Oils, Free Radicals, Oxidative Stress, Oxidised Fats, Polyunsaturated Fatty Acids, Saturated Fatty Acids | Comments Off on Oxidised Oils

Pycnogenol: Antioxidant Bark

Antioxidants are protective of disease because they inhibit free radical chain reactions, and this reduces oxidative stress. Oxidative stress is associated with many Western lifestyle diseases including cancer, cardiovascular disease, type 2 diabetes, arthritis and obesity. Oxidative stress may initiate … Continue reading

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Vitamin C Requirement in Smokers

Free radicals are molecules with unpaired electrons, and this makes them unstable and reactive. Free radicals react with stable molecules and in the process electrons are transferred from the stable molecule to the radical. This stabilises the radical but in … Continue reading

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Free Radical Recycling and The Eye

Free radicals are chemicals that possess an unpaired electron in their outer orbital. This chemical structure makes them reactive and interaction with other chemicals can cause the free radical to gain an electron. Such interactions reduce and stabilise the free … Continue reading

Posted in Antioxidant, Carotenoids, Chalcones, Eyes, Flavonoids, Free Radicals, Glutathione, Glutathione peroxidase, Inflammation, Stilbenes, Terpenes, Vitamin C, Vitamin E | Comments Off on Free Radical Recycling and The Eye