Category Archives: Fatty Acids

Caffeine and Insulin Sensitivity

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Fat Intolerance and Inflammation

The metabolic syndrome is a cluster of metabolic dysfunctions characterised by central and peripheral insulin resistance. Insulin resistance is a condition whereby the cells of the body become insensitive to the action of insulin and as a result less of … Continue reading

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Malonyl-CoA: Pivotal In Insulin Resistance?

Malonyl-CoA is an intermediate in the de novo synthesis of fatty acids. Stimulation of the de novo lipogenesis pathway therefore increases the production of malonyl-CoA. Malonyl-CoA is an important intermediate in this pathway because it allosterically inhibits a number of … Continue reading

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Acetyl L-Carnitine Improves Glucose Control

L-carnitine is a non-essential nonproteinaceous amino acid in human nutrition. L-carnitine is manufactured in humans, but can be ingested in the diet, with good sources being animal flesh. L-carnitine is involved in the transport of long chain fatty acids into … Continue reading

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Free Fatty acids and Insulin Resistance

Insulin resistance is thought to be a primary contributory factor in the development of obesity. Evidence supports the contention that increased accumulation of free fatty acids in tissues, as typified by elevated blood levels, are a significant contributory cause of … Continue reading

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Inflammation and insulin resistance

Oxidative stress is associated with insulin resistance. One of the possible drivers of oxidative stress is inflammation. Evidence shows that the obese have raised levels of inflammatory cytokines and chemokines in the plasma and in tissues. This may explain the … Continue reading

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Cooking With Fats

Posted in Fat, Fatty Acids, Hydrogenated Vegetable Oil, Monounsaturated Fatty Acids, Oxidised Fats, Polyunsaturated Fatty Acids, Saturated Fatty Acids, Trans Fatty Acids | Comments Off on Cooking With Fats

Insulin Resistance and Nonalcoholic Fatty Liver

Nonalcoholic fatty liver disease (NAFLD) is a recently identified phenomenon, whereby the liver becomes diseased through a mechanisms that is independent of alcohol consumption. Nonalcoholic fatty liver disease is almost identical pathologically to alcoholic fatty liver disease, but while the … Continue reading

Posted in Fatty Acids, Fructose, Insulin Resistance, Metabolic Syndrome, Non-alcoholic Fatty Liver Disease, Obesity, Triglycerides / Triacylglycerols | Comments Off on Insulin Resistance and Nonalcoholic Fatty Liver

Plasma Free Fatty Acids and Insulin Resistance

Plasma free fatty acids are raised in cases of obesity, and this may occur for a number of reasons. However, the cause and effect are not fully understood, and it is not clear if the raised levels of free fatty … Continue reading

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Fat As A Storage Compound

Fatty acids are a group of non-polar (non-water soluble) molecules that comprise of a carbon chain with a hydroxyl group and oxygen molecule at one end and a methyl group at the other. The chain lengths vary, but generally the … Continue reading

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