Category Archives: de Novo Lipogenesis

Low Carbohydrate Diets Lower Fasting Plasma Triglycerides

Low carbohydrates diets appear to be effective in treating obesity. This may relate to the ability of such diets to improve insulin sensitivity. If this hypothesis is correct, it would be expected that such diets would be effective because they … Continue reading

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Palmitoleic Acid: Marker of Metabolic Syndrome and Cancer Risk

Stearoyl CoA desaturase (Δ9 desaturase) is an enzyme that participates in the de novo lipogenesis pathway. This pathway is tasked with the creation of new fatty acids from non-fat sources. The pathway operate primarily in the liver and the substrate … Continue reading

Posted in Cancer, de Novo Lipogenesis, Monounsaturated Fatty Acids, Palmitoleic Acid, Saturated Fatty Acids | Comments Off on Palmitoleic Acid: Marker of Metabolic Syndrome and Cancer Risk

The Benefits of Refined Fructose Post-Workout

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Why Is Honey Superior to Sugar?

Sugar is increasingly being seen as a cause of Western lifestyle diseases, particularly obesity. As obesity develops the risk of other lifestyle diseases such as type 2 diabetes, cardiovascular disease and cancer also increase. Refined crystalline sugar, also called sucrose … Continue reading

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Is Coffee Protective of Insulin Resistance?

Refined crystalline sugar induces insulin resistance in mammals. Rat experiments have shown that feeding fructose at high intakes causes insulin resistance in just a few short weeks (here, here and here). Fructose can induce insulin resistance because it increases flux … Continue reading

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Fructose and Hypertriglyceridaemia

Diets containing more than 15 % refined crystalline fructose have been shown to increase fasting and postprandial triglyceride levels. This rise in plasma triglyceride levels may play a role in insulin resistance, and raised triglyceride levels are in turn a … Continue reading

Posted in Cardiovascular Disease, de Novo Lipogenesis, Fructose, High Fructose Corn Syrup, Insulin Resistance, Lipoproteins, Sucrose, Sugar, Triglycerides / Triacylglycerols, VLDL | Comments Off on Fructose and Hypertriglyceridaemia

Essential Fat Deficiency, Liver Overload Syndrome and The Metabolic Syndrome

The metabolic syndrome is a cluster of metabolic disorders characterised by insulin resistance. It is becoming increasingly evident that the Western diet is the cause of metabolic syndrome, and this results largely from the poor quality food that it contains. … Continue reading

Posted in Alpha Linolenic Acid, de Novo Lipogenesis, Delta 6-desaturase, Essential Fatty Acids, Glycaemia, Insulin Resistance, Linoleic Acid, Palmitoleic Acid, Western Diet | Comments Off on Essential Fat Deficiency, Liver Overload Syndrome and The Metabolic Syndrome

Why Farmers Feed Cattle High Grain Diets

It is ingrained in the psyche of the Western population that dietary saturated fat and cholesterol are the causes of cardiovascular disease. It is also ingrained in the psyche of Western populations that dietary fat will make you fat. This … Continue reading

Posted in Carbohydrate, de Novo Lipogenesis, Insulin Resistance, Obesity, Starch, Triglycerides / Triacylglycerols, VLDL, Weight Loss, Western Diet, Whole Grains | Comments Off on Why Farmers Feed Cattle High Grain Diets

Normal appetite Regulation

Posted in Abdominal Obesity, de Novo Lipogenesis, Fructose, Obesity, Traditional Diets, Weight Loss, Western Diet | Comments Off on Normal appetite Regulation

Is Fructose a Liver Toxin?

The damage that excessive alcohol consumption can cause to the liver is well understood. The ectopic stenosis that drives the liver damage associated with excessive alcohol consumption is caused by aberrations to the metabolism of fats and also to the … Continue reading

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