Category Archives: Creatine

The Functions of Glycine

Posted on March 15, 2024 by Robert Barrington

Glycine represents around 11.5 % of the total amino acids in humans and roughly 20 % of the nitrogen from amino acids in proteins. However, glycine is not essential because it can be synthesised from other chemicals including choline, glyoxylate … Continue reading →

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Glycine Supplements Increase Creatine Stored

Posted on August 2, 2023 by Robert Barrington

Glycine has been used to treat schizophrenia effectively as oral glycine is able to improve glutamate neurotransmission in the brain, suggesting that glycine is able to enter the brain across the blood brain barrier, and here have an effect on … Continue reading →

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Creatine Transport

Posted on January 21, 2021 by Robert Barrington

Creatine is synthesised in the liver and kidney. From here the creatine is transported to where it is required, mainly the skeletal muscle and brain. Creatine passes into the blood from the sites of synthesis and then into cells down … Continue reading →

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Creatine Synthesis 

Posted on January 21, 2021 by Robert Barrington

Dietary creatine from a typical mixed diet is equivalent to around 1 gram per day with a further 1 gram per day synthesised mainly in the liver and kidney. Creatine is synthesised from the amino acids glycine, arginine and methionine. … Continue reading →

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Creatine Monohydrate And Membrane Stabilisation

Posted on January 20, 2021 by Robert Barrington

Creatine monohydrate has a number of less well known pharmacological effects in cells. In this regard it is considered that creatine may have the ability to stabilise cell membranes. Creatine accumulates in cells where it can act as a zwitterion … Continue reading →

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More on the Insulin Creatine Connection

Posted on January 18, 2021 by Robert Barrington

Creatine monohydrate supplements have become popular with athletes because they can confer strength gains. Studies suggest that creatine monohydrate absorption and uptake are dependent on the function of the insulin system. In this regard insulin may be required for the … Continue reading →

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Creatine Monohydrate Stimulates Protein Synthesis

Posted on January 18, 2021 by Robert Barrington

The most well known explanation for the performance enhancing effect of creatine monohydrate is that it allows improvements in energy metabolism by causing accumulation of creatine in skeletal muscle, which increases the buffering capacity for ATP. However, there may be … Continue reading →

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Can Creatine Monohydrate Cause Insulin Resistance?

Posted on January 15, 2021 by Robert Barrington

Creatine monohydrate is a dietary supplement that can supply the body with creatine. This creatine can accumulate in skeletal muscle tissue and here can increase the formation of phosphocreatine. High skeletal muscle phosphocreatine stores may have ergogenic benefits because they … Continue reading →

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Vegan Athletes: Creatine and Beta-Alanine

Posted on November 23, 2020 by Robert Barrington

Veganism can be a healthy way to eat if extreme care is taken to maximise nutrient intake. The main pitfall associated with vegan diets is that because the diets are by their nature limiting diets, they may not contain a … Continue reading →

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Does Creatine Cause Subcutaneous Water Retention?

Posted on November 3, 2020 by Robert Barrington

Creatine monohydrate is a dietary supplement that increases the muscle content of creatine phosphate. The accumulation of creatine in muscle tissue is interesting because the resultant creatine phosphate stores may allow a more prolonged contraction cycle from the muscle, particularly … Continue reading →

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