Category Archives: Carnitine

Lysine, Vitamin B6 and Carnitine: Blood Lipids

Hyperlipidaemia is a condition characterised by high levels of certain lipids in the blood. The cause of hyperlipidaemia is a dysfunctional metabolism centreing on insulin resistance and fatty liver disease. The consequences of hyperlipidaemia are the development of cardiovascular disease. … Continue reading

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L-Carnitine Supplements For Athletes

L-carnitine is a substance produced naturally in the body, but which can be found in the diet in sources of meat. This relates to the main tissue concentration of carnitine which is in muscle tissue. The main physiological function of … Continue reading

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L-Carnitine Absorption and Metabolism 

L-carnitine is a nutrient factor synthesised by mammals and found mainly in muscle, kidney, liver and brain tissue. The total L-carnitine pool in mammals including humans is made up of L-carnitine as well as acylcarnitine esters of which acetyl-L-carnitine is … Continue reading

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L-Carnitine Absorption

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Acetyl L-Carnitine Improves Glucose Control

L-carnitine is a non-essential nonproteinaceous amino acid in human nutrition. L-carnitine is manufactured in humans, but can be ingested in the diet, with good sources being animal flesh. L-carnitine is involved in the transport of long chain fatty acids into … Continue reading

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Carnitine Deficiency, Fatty Liver and Weight Loss

Many people are aware of the damage that long-term ethanol (alcohol) consumption can have on the liver. The reason that ethanol can damage liver tissue is because the metabolism of ethanol can cause the deposition of lipids, mainly triglycerides, in … Continue reading

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Carnitine Supplements: Beneficial or Not?

Carnitine is a trimethylated amino acid derivative that is required in humans for the transport of fatty acids into mitochondria for β-oxidation. Based on this role, carnitine is sold as a dietary supplement for increasing fat oxidation (fat burning). However, … Continue reading

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Muscle Carnitine in Vegetarians

L-carnitine is a quaternary ammonium compound required for the transport of fatty acids into mitochondria for oxidation. Carnitine is synthesised endogenously from lysine and methionine with total synthesis producing roughly ≤1µmol L-carnitine per kg body mass per day. However, 2 … Continue reading

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Carnitine in Obesity

Carnitine (3-hydroxy-4-trimethylaminobutyrate) is required for the transport of long chain fatty acids into the mitochondria for oxidation. Carnitine palmitoyltransferase (CPT) catalyses the removal of coenzyme A from the activated fatty acids and replaces it with carnitine. Carnitine then shuttles the … Continue reading

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