Zinc and copper are essential minerals that are known to antagonise each other. In this respect high intakes of copper can inhibit the absorption of zinc, and vice versa. Therefore a balance must be struck such that both minerals are taken in optimal amounts to ensure they can be absorbed sufficiently. Zinc therapy has been shown to be beneficial to those with anxiety and this may relate to a correction of the correct zinc to copper ratio. Studies have investigated the plasma zinc to copper ratio in individuals with anxiety in order to better understand the relationship between the zinc to copper ratio and mood disorders. In one study, a group of individuals with symptoms of anxiety had their blood analysed and the zinc to copper ratio determined. The results showed that subjects with anxiety had significantly higher levels of copper and lower levels of zinc compared to less anxious subjects. After zinc supplementation, the subjects experienced significant increases in plasma zinc and reductions in anxiety.
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